Crystal-storing histiocytosis

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Pseudo-Peritoneal Carcinomatosis Presentation of a Crystal-Storing Histiocytosis With an Unmutated Monoclonal κ Light Chain

Crystal-storing histiocytosis (CSH) is a rare complication of monoclonal gammopathies caused by accumulation of crystalline material inside macrophages, and it may result in a variety of clinical manifestations depending on the involved organs. Although immunoglobulin κ light chains (LCs) seem to be the most frequent pathogenic component, very few molecular data are currently available.A 69-yea...

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Clinical Neuropathology image 1-2015: Crystal-storing histiocytosis of the central nervous system

Crystalloid inclusions are rarely encountered within the central nervous system (CNS). Aside from the more common Hirano bodies and Rosenthal fibers, which occur within neurons and astrocytic processes, both being composed of cytoskeletal proteins, eosinophilic crystalloid inclusions have been recently described within oligodendrocytes in a case of adult-onset, complicated form of hereditary sp...

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Crystal storing histiocytosis clinically mimicking metastatic carcinoma: Report of a case and reviews of literature.

BACKGROUND Crystal storing histiocytosis (CSH) is a rare disorder characterized by accumulation of histiocytes containing crystalline material inclusions. This entity can be misdiagnosed as infection or tumor. We present a case of idiopathic CSH mimicking metastatic squamous cell carcinoma in a cervical lymph node and review of literature regarding this rare entity. METHODS AND RESULTS The pa...

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Crystal-storing histiocytosis is a rare clinical entity characterized by an increase in the number of abnormal histiocytes accompanied by accumulation of crystallized immunoglobulins. We describe the case of an 80-year-old man who presented with crystal-storing histiocytosis of the lung 13 years after receiving a diagnosis of gastric non-Hodgkin lymphoma (NHL ; clinical stage, Lugano IA). After...

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Crystal storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of crystalline material in the cytoplasm of histiocytes. Involvement of the central nervous system (CNS) with CSH is extremely rare. Herein, we report a case of crystal storing histiocytosis involving the CNS. Using immunohistochemistry and mass spectrometry we demonstrate that the disease resulted from an ...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2016

ISSN: 0085-2538

DOI: 10.1016/j.kint.2015.12.012